RAZAN 10mg & 20mg Tablets (Vonoprazan) | Pharma Services Group

RAZAN 10mg & 20mg Tablets contain Vonoprazan, an oral potassium-competitive acid blocker (P-CAB) used to reduce stomach acid and manage acid-related gastrointestinal conditions. The available product listing confirms RAZAN 10mg Tablet and RAZAN 20mg Tablet, both containing Vonoprazan, with a listed pack size of 20 tablets for each strength.

Vonoprazan provides potent and sustained suppression of gastric acid production and is used in conditions such as acid reflux, gastroesophageal reflux disease (GERD), erosive esophagitis and peptic ulcer disease. It may also be prescribed in combination with antibiotics as part of an H. pylori eradication regimen, depending on the treatment protocol. Vonoprazan is pharmacologically different from traditional proton pump inhibitors (PPIs), as it directly and reversibly inhibits the gastric H⁺/K⁺-ATPase potassium-binding site.

Available Strengths

The product list identifies both RAZAN strengths as Vonoprazan tablets.

Key Benefits

• Contains Vonoprazan, a potassium-competitive acid blocker (P-CAB).
• Available in 10mg and 20mg strengths.
• Provides potent gastric acid suppression.
• Used for acid reflux and heartburn.
• Used in the management of GERD.
• May be prescribed for erosive esophagitis.
• Used for certain gastric and duodenal ulcers.
• May form part of combination therapy for H. pylori eradication.
• Oral tablet formulation for convenient administration.

How It Works

Vonoprazan belongs to the potassium-competitive acid blocker (P-CAB) class. It inhibits the gastric H⁺/K⁺-ATPase proton pump by competitively blocking potassium binding, which is necessary for gastric acid secretion.

Unlike conventional PPIs, Vonoprazan does not require activation in an acidic environment before inhibiting the proton pump. This allows rapid and sustained suppression of gastric acid, helping control acid-related symptoms and supporting healing of acid-related damage.

Uses / Therapeutic Applications

RAZAN (Vonoprazan) may be prescribed for:

• Gastroesophageal reflux disease (GERD)
• Acid reflux
• Heartburn
• Erosive esophagitis
• Gastric ulcers
• Duodenal ulcers
• Acid-related gastrointestinal conditions
• H. pylori infection, as part of an appropriate combination treatment regimen
• Prevention of recurrence of certain acid-related ulcers, where clinically indicated

The exact indication and strength depend on the patient’s condition and the treatment regimen prescribed by a healthcare professional.

Directions for Use

Take RAZAN exactly as prescribed by your doctor or pharmacist. The appropriate strength—10mg or 20mg—depends on the indication and individual treatment requirements.

Swallow the tablet with water. It may be taken according to the prescribed schedule and does not require the same meal-dependent activation as traditional PPIs.

Do not change from 10mg to 20mg, or vice versa, without medical advice. When used for H. pylori eradication, Vonoprazan is generally prescribed together with specific antibiotics according to the healthcare professional’s regimen.

Precautions

• Use RAZAN under the guidance of a qualified healthcare professional.
• Tell your doctor if you have liver or kidney problems.
• Inform your healthcare professional about all prescription medicines, OTC medicines and supplements you take.
• Tell your doctor if you have unexplained weight loss, difficulty swallowing, persistent vomiting or recurrent gastrointestinal symptoms.
• Seek urgent medical attention for vomiting blood or black/tarry stools.
• Tell your doctor about any previous allergic reaction to Vonoprazan or similar medicines.
• Long-term acid suppression should be used under appropriate medical supervision.
• Do not self-medicate for persistent heartburn without proper evaluation.

Possible Side Effects

Possible side effects of Vonoprazan may include headache, diarrhea, constipation, abdominal discomfort, nausea and vomiting. Some patients may experience other gastrointestinal or laboratory-related changes.

If side effects are severe, persistent or unusual, consult your doctor or pharmacist.

Storage Instructions

• Store in a cool, dry place.
• Protect from excessive heat, moisture and direct sunlight.
• Keep tablets in their original packaging.
• Keep out of reach of children.
• Do not use after the expiry date.
• Follow the storage conditions printed on the product packaging.

Manufacturer / Product Information

Brand: RAZAN
Generic Name: Vonoprazan
Available Strengths: 10mg & 20mg
Dosage Form: Tablet
Drug Class: Potassium-Competitive Acid Blocker (P-CAB)
Therapeutic Category: Gastrointestinal / Acid Suppressant
Route: Oral
Pack Size Listed: 20’s for each strength

Manufacturer note: The available registered-product listing confirms RAZAN 10mg and 20mg as Vonoprazan tablets, but the source does not clearly identify the finished-product manufacturer. Therefore, the manufacturer should be verified from the physical RAZAN packaging before publishing a specific manufacturer name.

Product Specifications