Fosmol Sachet 3g – Single-Dose Oral Antibiotic for Urinary Tract Infections

Product Overview

Fosmol Sachet 3g is a high-potency, single-dose broad-spectrum oral antibiotic formulation containing Fosfomycin Trometamol (3g elemental Fosfomycin). Specifically engineered for the first-line treatment of acute, uncomplicated lower urinary tract infections (UTIs) such as acute cystitis, Fosmol delivers rapid bactericidal concentration directly to the urinary tract. By providing high, sustained active drug levels in urine for up to 48 hours following a single oral dose, Fosmol effectively clears sensitive bacterial pathogens—including multi-drug resistant Escherichia coli—while maximizing patient compliance.

Key Benefits

• Single-Dose Convenience: Eliminates long multi-day antibiotic courses with a single, highly effective oral dose.

• Rapid Urinary Eradication: Concentrates directly in the bladder to achieve high bactericidal levels within hours of ingestion.

• Effective Against Resistant Strains: Highly active against Extended-Spectrum Beta-Lactamase (ESBL)-producing E. coli and resistant urinary pathogens.

• Fast Symptom Relief: Quickly alleviates painful urination (dysuria), urinary frequency, urgency, and lower abdominal discomfort.

• High Mucosal Adhesion Inhibition: Prevents bacteria from adhering to the uroepithelial lining of the urinary tract.

How It Works

Fosmol Sachet 3g (Fosfomycin Trometamol) acts as a bactericidal agent by inhibiting the initial step of bacterial cell wall synthesis. It irreversibly inactivates the enzyme UDP-$N$-acetylglucosamine enolpyruvyl transferase (MurA), which catalyzes the formation of $N$-acetylmuramic acid—an essential building block of the peptidoglycan cell wall. Because it targets a unique step prior to the action of beta-lactams and fluoroquinolones, Fosmol lacks cross-resistance with other major antibiotic classes. Furthermore, it significantly reduces bacterial adherence to bladder mucosal walls.

Key Active Ingredients

• Fosfomycin Trometamol (equivalent to 3g Fosfomycin): Phosphonic acid derivative antibiotic designed for rapid absorption and prolonged urinary excretion.

Directions for Use

1. Preparation: Dissolve the entire contents of 1 sachet (3g) into half a glass (approx. 90-120 ml) of cold water or non-alcoholic beverage. Stir well until completely dissolved and consume immediately.

2. Administration: Take orally once, preferably on an empty stomach (2 hours before or 2 hours after a meal) and after emptying the bladder, ideally at bedtime.

3. Dosing:

   • Acute Uncomplicated Cystitis (Women 12+ years): Single 3g sachet.

   • Prophylaxis of UTI in Surgical/Diagnostic Procedures: One 3g sachet 3 hours prior to the procedure, followed by a second 3g sachet 24 hours post-procedure as advised by a physician.

Precautions

• Prescription-only medication; use strictly under medical supervision.

• Contraindications: Do not use in patients with severe renal impairment (CLcr​<10 ml/min) or known hypersensitivity to Fosfomycin.

• Co-administration with metoclopramide lowers serum and urinary concentrations of Fosfomycin; avoid taking simultaneously.

• May cause mild gastrointestinal disturbances such as transient diarrhea, nausea, or headache.

• Consult a physician before use during pregnancy or lactation.

• Keep out of reach of children.

Storage Instructions

Store in a cool, dry place below 30°C, protected from direct sunlight, heat, and moisture. Keep sachets sealed in their original outer packaging until consumption.

Manufacturer Information

Formulated and manufactured in strict compliance with international pharmaceutical quality standards, dedicated to engineering advanced anti-infective and urological therapies that ensure clinical efficacy, convenience, and rapid recovery.