Description
Product Overview
Corelex Capsules 4mg is an advanced antimuscarinic formulation containing Tolterodine Tartrate / Fesoterodine Fumarate (4mg), specifically engineered for the treatment of overactive bladder (OAB). Designed to target and relax the detrusor muscle of the urinary bladder, Corelex reduces urinary urgency, frequency, and urge incontinence. Its extended-release capsule delivery provides consistent therapeutic plasma concentrations over 24 hours, restoring bladder control and significantly improving quality of life for patients experiencing bladder instability.
Key Benefits
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Reduces Urinary Urgency & Frequency: Calms sudden, strong urges to urinate and decreases daytime and nighttime bathroom visits.
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Controls Urge Incontination: Helps prevent involuntary urinary leakage associated with bladder spasms.
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Increases Bladder Capacity: Relaxes the detrusor muscle, allowing the bladder to hold larger volumes of urine comfortably.
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24-Hour Continuous Relief: Extended-release capsule technology ensures smooth, round-the-clock symptom control with convenient once-daily dosing.
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Targeted Muscarinic Selectivity: Formulated to minimize common anticholinergic side effects such as severe dry mouth and dry eyes.
How It Works
Corelex Capsules 4mg function as a competitive, selective muscarinic receptor antagonist. In an overactive bladder, involuntary contractions of the detrusor smooth muscle are mediated by acetylcholine acting on muscarinic ( and ) receptors. Corelex selectively blocks these receptors, inhibiting acetylcholine-induced muscle contractions during the bladder filling phase. This increases maximum cystometric capacity, decreases detrusor pressure, and suppresses involuntary bladder spasms without impairing normal voluntary voiding.
Key Active Ingredients
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Antimuscarinic Active Agent (4mg): Selective muscarinic receptor antagonist that stabilizes bladder smooth muscle function and prevents involuntary contractions.
Directions for Use
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Administration: Swallow the capsule whole with a glass of water. Do not chew, crush, or open the capsule, as this disrupts the extended-release mechanism.
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Timing: Take once daily, with or without food, at the same time each day for optimal symptom control.
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Consistency: Take regularly as prescribed by your physician; optimal therapeutic benefits are typically observed after 2 to 4 weeks of continuous therapy.
Precautions
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Prescription-only medication; use strictly under medical supervision.
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Contraindications: Do not use in patients with urinary retention, gastric retention, or uncontrolled narrow-angle glaucoma.
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Exercise caution in patients with hepatic or severe renal impairment, gastrointestinal obstructive disorders, or myasthenia gravis.
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May cause mild drowsiness, blurred vision, or dizziness; exercise caution when driving or operating heavy machinery until reaction is known.
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Consult a physician before use during pregnancy or lactation.
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Keep out of reach of children.
Storage Instructions
Store in a cool, dry place below 30°C, protected from direct light, heat, and moisture. Keep capsules in their original blister packaging until ingestion.
Manufacturer Information
Formulated and manufactured in strict compliance with international pharmaceutical quality standards, dedicated to developing targeted urological solutions that enhance patient comfort, urinary health, and daily well-being.
Brand
Brand
PHARMASOL (PVT) LTD

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