Axoral-DS Suspension – Double-Strength Pediatric & Adult Antifungal Liquid

Product Overview

Axoral-DS (Double Strength) Suspension is a high-potency, broad-spectrum oral liquid antifungal formulation designed to eradicate moderate-to-severe cutaneous, mucosal, and systemic fungal infections. Delivering twice the active strength per unit dose compared to standard liquid strengths, Axoral-DS allows for lower dosing volumes while ensuring high therapeutic blood concentrations. It is especially suitable for pediatric patients, elderly individuals, and patients with dysphagia who require robust systemic antifungal treatment for recalcitrant candidiasis, tinea infections, and deep-seated fungal pathogens.

Key Benefits

• Double-Strength Formula: Delivers a higher concentration of active antifungal agent in smaller liquid volumes for improved compliance.

• Broad-Spectrum Fungicidal Action: Clears resistant strains of dermatophytes (Trichophyton, Microsporum), Candida species, and systemic fungi.

• Convenient Liquid Dosing: Ideal for children and adult patients who experience difficulty swallowing solid tablets or capsules.

• Rapid Systemic Absorption: Fast-acting oral liquid vehicle ensures quick systemic bioavailability to target infected tissues.

• Prevents Recrudescence & Relapse: Systematically eliminates fungal pathogens to minimize the risk of infection recurrence.

How It Works

Axoral-DS Suspension operates by inhibiting the fungal cytochrome P450-dependent enzyme 14α-demethylase. This blocks the cellular biosynthesis of ergosterol, an essential component of the fungal cell membrane. The severe depletion of ergosterol, alongside the accumulation of toxic precursor sterols, disrupts membrane permeability and structural integrity. This leads to cellular leakage, inhibition of fungal replication (fungistatic), and ultimate destruction of the fungal pathogen (fungicidal).

Key Active Ingredients

• Broad-Spectrum Antifungal Agent (Double-Strength): Highly concentrated active compound that halts ergosterol synthesis to eradicate fungal pathogens systemically.

Directions for Use

1. Preparation: Shake the bottle thoroughly before each use to ensure even suspension of the active ingredient.

2. Measurement: Use the calibrated measuring cup or oral dosing syringe provided to measure the exact prescribed dose.

3. Administration: Take orally, preferably during or immediately after a main meal to maximize gastrointestinal absorption.

4. Duration: Complete the entire course of therapy as directed by your physician to prevent resistance and clinical relapse.

Precautions

• Prescription-only drug; administer strictly under the guidance of a licensed healthcare professional.

• Use caution and monitor liver function tests in patients with pre-existing hepatic impairment or those undergoing extended treatment courses.

• Inform your physician of all concomitant medications to screen for potential cytochrome P450 drug interactions.

• Consult a doctor before use during pregnancy or lactation.

• Keep out of reach of children.

Storage Instructions

Store in a cool, dry place below 30°C, protected from direct sunlight, heat, and moisture. Keep the bottle tightly capped when not in use. Do not freeze.

Manufacturer Information

Formulated and manufactured in strict compliance with international pharmaceutical quality standards, dedicated to engineering advanced anti-infective formulations designed to safeguard patient health and promote fast clinical recovery.