Olanzaget Tablets 3mg/25mg | Olanzapine & Fluoxetine for Bipolar Depression & Treatment-Resistant Depression | Pharma Services Group

Olanzaget Tablets 3mg/25mg contain a combination of Olanzapine and Fluoxetine, prescribed for the treatment of depressive episodes associated with Bipolar I Disorder and treatment-resistant depression in adults. This prescription medicine combines an atypical antipsychotic, Olanzapine, with an antidepressant, Fluoxetine, to provide a dual-action approach to specific depressive conditions. Fluoxetine primarily works by increasing serotonin activity in the central nervous system through inhibition of serotonin reuptake, while Olanzapine acts on several neurotransmitter receptors, including dopamine and serotonin receptors. Olanzaget should only be used under the supervision and prescription of a qualified healthcare professional.

Key Benefits

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• Contains Olanzapine and Fluoxetine
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• Indicated for depressive episodes associated with Bipolar I Disorder in adults
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• Indicated for treatment-resistant Major Depressive Disorder in adults
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• Combines antidepressant and antipsychotic activity
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• Supports regulation of serotonin and dopamine neurotransmitter activity
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• Convenient oral tablet formulation
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How It Works

Fluoxetine is a selective serotonin reuptake inhibitor (SSRI) that inhibits serotonin reuptake in the central nervous system, increasing serotonin availability between nerve cells.

Olanzapine is an atypical antipsychotic that acts as an antagonist at several dopamine and serotonin receptors, along with other receptor systems. Together, the two active ingredients provide complementary pharmacological effects for the specific depressive conditions for which this combination is prescribed.

Indications

Olanzaget is indicated for the acute treatment of:

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• Depressive episodes associated with Bipolar I Disorder in adults
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• Treatment-resistant depression (Major Depressive Disorder) in adults who have not responded adequately to two separate antidepressant treatment trials of appropriate dose and duration during the current episode.
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Directions for Use

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• Take Olanzaget exactly as prescribed by your physician.
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• The dosage and treatment duration depend on the patient's condition and clinical response.
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• Take the tablet orally according to your physician's instructions.
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• Do not change the dose or discontinue treatment without medical advice.
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• Do not use this medicine for self-treatment of depression.
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Precautions

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• Olanzaget is a prescription-only medicine.
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• Patients receiving antidepressant treatment should be monitored for worsening depression, suicidal thoughts, unusual behavior, or significant changes in mood, particularly during the initial stages of treatment or following dosage changes.
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• Inform your doctor about all medicines and supplements you are taking.
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• Tell your healthcare provider if you have liver problems, cardiovascular conditions, seizures, or other significant medical conditions.
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• Consult your physician before use during pregnancy or breastfeeding.
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• Avoid stopping treatment suddenly unless instructed by your healthcare professional.
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Contraindications

Olanzaget should not be used in patients with:

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• Hypersensitivity to Olanzapine, Fluoxetine, or any component of the formulation
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• Concurrent use of Monoamine Oxidase Inhibitors (MAOIs)
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• Concurrent use of Pimozide
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• Concurrent use of Thioridazine
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Appropriate washout periods may be required when switching between certain medicines. Always follow your physician's instructions.

Possible Side Effects

Possible adverse effects may include nausea, vomiting, diarrhea, gastrointestinal discomfort, changes in weight, edema, dizziness, changes in blood counts, and other effects.

More serious or clinically significant reactions may occur in some patients. Seek prompt medical attention for severe or unusual symptoms, significant behavioral changes, or suicidal thoughts.

Drug Interactions

Olanzaget may interact with various medicines, including:

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• MAO inhibitors
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• Serotonergic medicines
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• Triptans
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• Tryptophan
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• NSAIDs, aspirin, warfarin and other medicines affecting blood clotting
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• Benzodiazepines
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• Pimozide
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• Thioridazine
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• Carbamazepine
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• Tricyclic antidepressants
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• Antihypertensive medicines
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• Levodopa and dopamine agonists
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• Clozapine
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• Haloperidol
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• Phenytoin
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• Lithium
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• Valproate
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• Theophylline
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• Other medicines affecting CYP enzymes
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Always provide your healthcare professional with a complete list of medicines you use before starting treatment.

Ingredients

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• Olanzapine
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• Fluoxetine
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Strength: 3mg/25mg combination as specified for the product.

Pack Information

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• 1 Box = 2 Strips
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• 1 Strip = 7 Tablets
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• Total = 14 Tablets per Box
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Prescription Status

Prescription Required: YES

Storage Instructions

Store Olanzaget Tablets at room temperature, away from direct light, excessive heat, and moisture. Keep the medicine out of reach of children. Follow any additional storage instructions provided on the product packaging.

Product Specifications