DESTON 8mg Tablet contains Ondansetron 8mg, a 5-HT3 receptor antagonist used to help prevent and control nausea and vomiting.

It works by blocking serotonin signals that can trigger the vomiting reflex. DESTON 8mg is an oral antiemetic medicine commonly used when nausea and vomiting occur in connection with certain medical treatments and procedures. The attached product pack shows DESTON 8mg, Ondansetron HCl USP, in a pack of 10 tablets.

Ondansetron 8mg tablets are particularly associated with the prevention and treatment of nausea and vomiting related to chemotherapy, radiotherapy and postoperative recovery, according to clinical prescribing information for ondansetron. DESTON should be used according to the healthcare professional's instructions, particularly because the appropriate dose and treatment duration depend on the underlying cause of nausea and vomiting.

Key Benefits

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• Helps prevent and control nausea and vomiting.
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• Contains Ondansetron 8mg.
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• Belongs to the 5-HT3 receptor antagonist class of antiemetic medicines.
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• Oral tablet formulation for convenient administration.
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• Commonly used in the management of treatment-related nausea and vomiting.
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• Suitable for use when prescribed by a qualified healthcare professional.
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How It Works

Ondansetron selectively blocks 5-HT3 serotonin receptors in the gastrointestinal tract and central nervous system. By reducing serotonin-mediated signals involved in the vomiting reflex, it helps decrease nausea and vomiting.

Directions for Use

Take DESTON 8mg exactly as directed by your doctor or pharmacist. The appropriate dose and frequency vary according to the condition being treated, age, other medicines and individual health factors. Do not increase the dose or take it more frequently than prescribed.

For chemotherapy-, radiotherapy- or surgery-related nausea and vomiting, follow the specific dosing schedule provided by your healthcare professional.

Precautions

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• Do not use Ondansetron if you have a known allergy to ondansetron or other 5-HT3 receptor antagonists.
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• Inform your doctor if you have a history of heart rhythm problems or prolonged QT interval.
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• Tell your healthcare professional about all medicines and supplements you are taking.
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• Use with caution if you have significant electrolyte abnormalities or liver problems.
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• Seek medical attention for severe allergic symptoms, fainting, abnormal heartbeat or other serious reactions.
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• DESTON is an antiemetic and should not be used to self-treat persistent vomiting without determining the underlying cause.
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Possible Side Effects

Some people may experience headache, constipation, dizziness or a feeling of warmth/flushing. More serious heart-rhythm effects, including QT prolongation, can occur in susceptible individuals, so medical advice is important when risk factors are present.

Storage Instructions

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• Store in a cool, dry place.
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• Protect from excessive heat, moisture and direct sunlight.
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• Keep the medicine in its original packaging.
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• Keep out of reach of children.
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• Check the expiry date before use.
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Manufacturer Information

Manufacturer: Pharmasol (Pvt.) Ltd., Pakistan \nBrand: DESTON \nGeneric Name: Ondansetron \nTherapeutic Class: Antiemetic / 5-HT3 receptor antagonist

Government procurement records identify DESTON Tablets 8mg as an Ondansetron 8mg product manufactured by Pharmasol in Lahore.

Product Specifications