{"product_id":"vancosol-injection-500mg-1g-glycopeptide-antibacterial-therapy-for-severe-resistant-infections","title":"Vancosol Injection (500mg \u0026 1g) - Glycopeptide Antibacterial Therapy for Severe Resistant Infections","description":"\u003cdiv class=\"container\"\u003e\r\\n\u003cdiv id=\"model-response-message-contentr_6bf9b88f80dd9785\" class=\"markdown markdown-main-panel md-content enable-luminous-fast-follows enable-updated-hr-color tutor-markdown-rendering\" dir=\"ltr\" aria-busy=\"false\" aria-live=\"polite\"\u003e\r\\n\u003ch2 data-path-to-node=\"11\"\u003eProduct Overview\u003c\/h2\u003e\r\\n\u003cp data-path-to-node=\"12\"\u003e\u003cb data-path-to-node=\"12\" data-index-in-node=\"0\"\u003eVancosol Injection\u003c\/b\u003e is a potent, broad-spectrum parenteral glycopeptide antibacterial formulation containing \u003cb data-path-to-node=\"12\" data-index-in-node=\"108\"\u003eVancomycin Hydrochloride\u003c\/b\u003e. Formulated for slow Intravenous (IV) infusion, Vancosol serves as a critical first-line antibiotic for severe, complicated, and multi-drug-resistant Gram-positive bacterial infections. It is specifically indicated for the management of infections caused by \u003cb data-path-to-node=\"12\" data-index-in-node=\"391\"\u003eMethicillin-Resistant \u003ci data-path-to-node=\"12\" data-index-in-node=\"413\"\u003eStaphylococcus aureus\u003c\/i\u003e (MRSA)\u003c\/b\u003e and co-agulase-negative staphylococci, including severe sepsis, infective endocarditis, lower respiratory tract infections (nosocomial pneumonia), bone and joint infections (osteomyelitis), complicated skin and soft tissue structure infections, and catheter-related bloodstream infections.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"13\"\u003eKey Benefits\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"14\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,0,0\"\u003e\u003cb data-path-to-node=\"14,0,0\" data-index-in-node=\"0\"\u003eGold Standard Against MRSA:\u003c\/b\u003e Unmatched bactericidal efficacy against Methicillin-Resistant \u003ci data-path-to-node=\"14,0,0\" data-index-in-node=\"90\"\u003eStaphylococcus aureus\u003c\/i\u003e and resistant enterococcal strains.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,1,0\"\u003e\u003cb data-path-to-node=\"14,1,0\" data-index-in-node=\"0\"\u003eTargeted Inpatient Critical Care:\u003c\/b\u003e Primary therapy for severe hospital-acquired pneumonia, septicemia, and complicated prosthetic joint infections.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,2,0\"\u003e\u003cb data-path-to-node=\"14,2,0\" data-index-in-node=\"0\"\u003eEssential Alternative for Beta-Lactam Hypersensitivity:\u003c\/b\u003e Provides vital anti-staphylococcal and anti-streptococcal coverage in patients with severe penicillin\/cephalosporin allergies.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,3,0\"\u003e\u003cb data-path-to-node=\"14,3,0\" data-index-in-node=\"0\"\u003eHigh Tissue Concentration:\u003c\/b\u003e Achieves effective bactericidal concentrations in heart valves, bone, pulmonary tissue, and peritoneal fluid.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,4,0\"\u003e\u003cb data-path-to-node=\"14,4,0\" data-index-in-node=\"0\"\u003eFlexible Dosing Strengths (500mg \u0026amp; 1g):\u003c\/b\u003e Facilitates precise body-weight and therapeutic drug monitoring (TDM) dosage adjustments.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"15\"\u003eHow It Works\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"16\"\u003eVancosol Injection (Vancomycin HCl) exerts its bactericidal effect by binding with high affinity to the \u003cb data-path-to-node=\"16\" data-index-in-node=\"104\"\u003eD-alanyl-D-alanine terminus\u003c\/b\u003e of cell wall peptidoglycan precursors. This binding sterically inhibits the transglycosylation and transpeptidation steps required for peptidoglycan polymerization and cross-linking, causing structural failure of the bacterial cell wall. Additionally, Vancomycin alters bacterial cell membrane permeability and selectively inhibits RNA synthesis, providing multi-target bactericidal activity against dividing Gram-positive bacteria.\u003c\/p\u003e\r\\n\r\\n\u003ch2 data-path-to-node=\"18\"\u003eWooCommerce Attribute \/ Variation Details\u003c\/h2\u003e\r\\n\u003ch3 data-path-to-node=\"19\"\u003eVariation 1: VANCOSOL INJ 500MG\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"20\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,0,0\"\u003e\u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"0\"\u003eSKU:\u003c\/b\u003e \u003ccode data-path-to-node=\"20,0,0\" data-index-in-node=\"5\"\u003eVAN-INJ-500\u003c\/code\u003e\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,1,0\"\u003e\u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"0\"\u003eShort Description:\u003c\/b\u003e Ideal for pediatric regimens, step-down maintenance dosing, and precise dose titration in patients with renal impairment.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,2,0\"\u003e\u003cb data-path-to-node=\"20,2,0\" data-index-in-node=\"0\"\u003eKey Active Ingredient:\u003c\/b\u003e Vancomycin Hydrochloride — equivalent to 500mg Vancomycin per vial.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,3,0\"\u003e\u003cb data-path-to-node=\"20,3,0\" data-index-in-node=\"0\"\u003eTarget Indications:\u003c\/b\u003e Pediatric MRSA infections, weight-adjusted dosing, and dose-modified regimens for compromised renal clearance.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,4,0\"\u003e\u003cb data-path-to-node=\"20,4,0\" data-index-in-node=\"0\"\u003eStandard Dosing:\u003c\/b\u003e Administered via slow IV infusion (over at least 60 minutes) every 6 to 12 hours based on therapeutic drug monitoring (TDM) serum trough levels.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"21\"\u003eVariation 2: VANCOSOL INJ 1G\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"22\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eSKU:\u003c\/b\u003e \u003ccode data-path-to-node=\"22,0,0\" data-index-in-node=\"5\"\u003eVAN-INJ-1G\u003c\/code\u003e\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eShort Description:\u003c\/b\u003e Standard adult clinical strength for acute inpatient management of severe MRSA bacteremia, nosocomial pneumonia, and endocarditis.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eKey Active Ingredient:\u003c\/b\u003e Vancomycin Hydrochloride — equivalent to 1g Vancomycin per vial.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,3,0\"\u003e\u003cb data-path-to-node=\"22,3,0\" data-index-in-node=\"0\"\u003eTarget Indications:\u003c\/b\u003e Severe MRSA sepsis, infective endocarditis, complicated osteomyelitis, hospital-acquired pneumonia, and surgical site infections.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,4,0\"\u003e\u003cb data-path-to-node=\"22,4,0\" data-index-in-node=\"0\"\u003eStandard Dosing:\u003c\/b\u003e Administered 1g via slow IV infusion (over at least 100 to 120 minutes) every 12 hours for adults with normal renal function.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch2 data-path-to-node=\"24\"\u003eGeneral Product Details (Shared across variations)\u003c\/h2\u003e\r\\n\u003ch3 data-path-to-node=\"25\"\u003eKey Active Ingredients\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"26\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eVancomycin Hydrochloride (500mg \/ 1g per vial):\u003c\/b\u003e Parenteral glycopeptide antibiotic that inhibits bacterial cell wall peptidoglycan synthesis in Gram-positive pathogens.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"27\"\u003eDirections for Use\u003c\/h3\u003e\r\\n\u003col start=\"1\" data-path-to-node=\"28\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e Reconstitute the dry powder vial by adding 10ml (for 500mg) or 20ml (for 1g) of Sterile Water for Injection to yield a 50mg\/ml solution.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"28,1,0\"\u003e\u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"0\"\u003eDilution:\u003c\/b\u003e Reconstituted solution \u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"33\"\u003emust be diluted further\u003c\/b\u003e in at least 100ml (for 500mg) or 200ml (for 1g) of 0.9% Sodium Chloride Injection or 5% Dextrose Injection to achieve a concentration of not more than 5mg\/ml.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"28,2,0\"\u003e\u003cb data-path-to-node=\"28,2,0\" data-index-in-node=\"0\"\u003eInfusion Rate \u0026amp; Route:\u003c\/b\u003e Strictly for \u003cb data-path-to-node=\"28,2,0\" data-index-in-node=\"36\"\u003eIntravenous (IV) Infusion\u003c\/b\u003e. Do NOT give via intramuscular or rapid bolus IV injection.\u003c\/p\u003e\r\\n\r\\n\u003cul data-path-to-node=\"28,2,1\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"28,2,1,0,0\"\u003eInfuse at a rate of \u003cb data-path-to-node=\"28,2,1,0,0\" data-index-in-node=\"20\"\u003eno more than 10mg\/min\u003c\/b\u003e (or over at least 60 minutes for 500mg, and at least 100–120 minutes for 1g).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"28,3,0\"\u003e\u003cb data-path-to-node=\"28,3,0\" data-index-in-node=\"0\"\u003eProfessional Healthcare Use:\u003c\/b\u003e Must be administered exclusively under direct medical supervision in a hospital setting with therapeutic drug monitoring (TDM) capabilities.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ol\u003e\r\\n\u003ch3 data-path-to-node=\"29\"\u003ePrecautions\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"30\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003ePrescription-Only Parenteral:\u003c\/b\u003e For inpatient hospital and specialized clinical administration only; strictly avoid self-administration.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003e\"Red Man Syndrome\" Warning:\u003c\/b\u003e Rapid IV bolus administration can trigger histamine release leading to severe hypotension, flushing, and a maculopapular rash on the face, neck, and upper torso. Always maintain slow infusion rates.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,2,0\"\u003e\u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"0\"\u003eOtotoxicity \u0026amp; Nephrotoxicity:\u003c\/b\u003e May cause hearing loss or renal failure, particularly when combined with other nephrotoxic\/ototoxic agents (e.g., aminoglycosides). Regular monitoring of serum renal function and serum Vancomycin trough levels is required.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,3,0\"\u003e\u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"0\"\u003eExtravasation Risk:\u003c\/b\u003e Infuse into a large vein or central line to avoid severe local tissue necrosis or thrombophlebitis.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,4,0\"\u003eConsult an attending physician before use during pregnancy or lactation.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,5,0\"\u003eKeep out of reach of children.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"31\"\u003eStorage Instructions\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"32\"\u003eStore the un-reconstituted dry powder vial below 30°C, protected from light and heat. Once reconstituted and diluted in compatible IV fluids, the solution is stable for 14 days under refrigeration (\u003cspan class=\"math-inline\" data-math=\"2^\\circ\\text{C}\" data-index-in-node=\"198\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord\"\u003e2\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e∘\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mord text\"\u003e\u003cspan class=\"mord\"\u003eC\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e to \u003cspan class=\"math-inline\" data-math=\"8^\\circ\\text{C}\" data-index-in-node=\"217\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord\"\u003e8\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e∘\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mord text\"\u003e\u003cspan class=\"mord\"\u003eC\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e) or 24 hours at room temperature (\u003cspan class=\"math-inline\" data-math=\"25^\\circ\\text{C}\" data-index-in-node=\"267\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord\"\u003e2\u003c\/span\u003e\u003cspan class=\"mord\"\u003e5\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e∘\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mord text\"\u003e\u003cspan class=\"mord\"\u003eC\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e). Do not freeze.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"33\"\u003eManufacturer Information\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"34\"\u003eFormulated and manufactured in strict compliance with international pharmaceutical quality standards, dedicated to engineering essential anti-infective parenteral formulations to fight drug-resistant pathogens and safeguard inpatient recovery.\u003c\/p\u003e\r\\n\r\\n\u003c\/div\u003e\r\\n\u003c\/div\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":44164490887227,"sku":null,"price":0.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0695\/4899\/8715\/files\/VANCOSL-500-INJ.jpg?v=1789027893","url":"https:\/\/pharmaservicesgroup.com\/products\/vancosol-injection-500mg-1g-glycopeptide-antibacterial-therapy-for-severe-resistant-infections","provider":"Pharma Services Distribution","version":"1.0","type":"link"}