{"product_id":"promiz-injection-40mg-intravenous-omeprazole-acid-suppression-therapy","title":"Promiz Injection 40mg - Intravenous Omeprazole Acid Suppression Therapy","description":"\u003cspan style=\"color: #000000; font-size: 44px; font-weight: 600;\"\u003eProduct Overview\u003c\/span\u003e\r\\n\u003cdiv class=\"container\"\u003e\r\\n\u003cdiv id=\"model-response-message-contentr_9a7e67bcad744308\" class=\"markdown markdown-main-panel md-content enable-luminous-fast-follows enable-updated-hr-color tutor-markdown-rendering\" dir=\"ltr\" aria-busy=\"false\" aria-live=\"polite\"\u003e\r\\n\u003cp data-path-to-node=\"10\"\u003e\u003cb data-path-to-node=\"10\" data-index-in-node=\"0\"\u003ePromiz Injection 40mg\u003c\/b\u003e is a high-potency parenteral Proton Pump Inhibitor (PPI) formulation containing \u003cb data-path-to-node=\"10\" data-index-in-node=\"102\"\u003eOmeprazole Sodium (40mg per vial)\u003c\/b\u003e. Engineered for immediate systemic bioavailability via Intravenous (IV) injection or infusion, Promiz Injection delivers rapid and sustained inhibition of gastric acid secretion. It is indicated for the acute management of Gastroesophageal Reflux Disease (GERD) with esophagitis, gastric and duodenal ulcers when oral therapy is inappropriate or non-feasible, stress ulcer prophylaxis in critically ill patients, and the prevention of rebleeding following endoscopic treatment of acute peptic ulcer hemorrhages.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"11\"\u003eKey Benefits\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"12\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,0,0\"\u003e\u003cb data-path-to-node=\"12,0,0\" data-index-in-node=\"0\"\u003eRapid \u0026amp; Potent Acid Suppression:\u003c\/b\u003e Achieves immediate systemic action to elevate intragastric pH in acute and critical clinical settings.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,1,0\"\u003e\u003cb data-path-to-node=\"12,1,0\" data-index-in-node=\"0\"\u003eEffective Peptic Ulcer Hemostasis:\u003c\/b\u003e Maintains high intragastric pH (\u003cspan class=\"math-inline\" data-math=\"\u0026gt;6.0\" data-index-in-node=\"67\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mrel\"\u003e\u0026gt;\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord\"\u003e6.0\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e) to promote blood clot stabilization and lower the risk of recurrent peptic ulcer rebleeding.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,2,0\"\u003e\u003cb data-path-to-node=\"12,2,0\" data-index-in-node=\"0\"\u003eEssential Inpatient Alternative:\u003c\/b\u003e Serves as a reliable parenteral option for surgical, unconscious, NPO (nothing by mouth), or severely dysphagic patients.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,3,0\"\u003e\u003cb data-path-to-node=\"12,3,0\" data-index-in-node=\"0\"\u003eICU Stress Ulcer Prophylaxis:\u003c\/b\u003e Protects critically ill patients from acute upper gastrointestinal mucosal lesions and bleeding.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,4,0\"\u003e\u003cb data-path-to-node=\"12,4,0\" data-index-in-node=\"0\"\u003eTargeted 24-Hour Control:\u003c\/b\u003e Sustains elevated intragastric pH levels to facilitate rapid esophageal and mucosal ulcer healing.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"13\"\u003eHow It Works\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"14\"\u003ePromiz Injection 40mg (Omeprazole Sodium) acts as a targeted, irreversible inhibitor of the gastric \u003cb data-path-to-node=\"14\" data-index-in-node=\"100\"\u003e\u003cspan class=\"math-inline\" data-math=\"H^+\/K^+\" data-index-in-node=\"100\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord mathnormal\"\u003eH\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\/\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord mathnormal\"\u003eK\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e-ATPase enzyme system\u003c\/b\u003e (the proton pump) located on the secretory membrane of parietal cells. Following IV administration, Omeprazole diffuses into the acidic canaliculi of gastric parietal cells, where it is converted into its active sulfenamide metabolite. This active form binds covalently to the cysteine residues of the \u003cspan class=\"math-inline\" data-math=\"H^+\/K^+\" data-index-in-node=\"431\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord mathnormal\"\u003eH\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\/\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord mathnormal\"\u003eK\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e-ATPase enzyme, blocking the final step of gastric acid secretion and inhibiting both basal and stimulated acid release regardless of the secretagogue stimulus.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"15\"\u003eKey Active Ingredients\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"16\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"16,0,0\"\u003e\u003cb data-path-to-node=\"16,0,0\" data-index-in-node=\"0\"\u003eOmeprazole Sodium (equivalent to 40mg Omeprazole per vial):\u003c\/b\u003e Intravenous substituted benzimidazole proton pump inhibitor that blocks parietal cell \u003cspan class=\"math-inline\" data-math=\"H^+\/K^+\" data-index-in-node=\"146\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord mathnormal\"\u003eH\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\/\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord mathnormal\"\u003eK\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mbin mtight\"\u003e+\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e-ATPase to suppress gastric acid release.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"17\"\u003eDirections for Use\u003c\/h3\u003e\r\\n\u003col start=\"1\" data-path-to-node=\"18\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"18,0,0\"\u003e\u003cb data-path-to-node=\"18,0,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e Reconstitute the 40mg dry powder vial with 10ml of 0.9% Sodium Chloride Injection or 5% Dextrose for slow IV injection, or dilute further in 100ml of compatible IV solution for IV infusion.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"18,1,0\"\u003e\u003cb data-path-to-node=\"18,1,0\" data-index-in-node=\"0\"\u003eAdministration:\u003c\/b\u003e\u003c\/p\u003e\r\\n\r\\n\u003cul data-path-to-node=\"18,1,1\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"18,1,1,0,0\"\u003e\u003cb data-path-to-node=\"18,1,1,0,0\" data-index-in-node=\"0\"\u003eIV Injection:\u003c\/b\u003e Administer the reconstituted solution slowly over a period of \u003cb data-path-to-node=\"18,1,1,0,0\" data-index-in-node=\"76\"\u003eat least 2.5 to 5 minutes\u003c\/b\u003e (maximum rate of 4ml per minute).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"18,1,1,1,0\"\u003e\u003cb data-path-to-node=\"18,1,1,1,0\" data-index-in-node=\"0\"\u003eIV Infusion:\u003c\/b\u003e Infuse diluted solution over \u003cb data-path-to-node=\"18,1,1,1,0\" data-index-in-node=\"42\"\u003e20 to 30 minutes\u003c\/b\u003e.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"18,1,1,2,0\"\u003e\u003cb data-path-to-node=\"18,1,1,2,0\" data-index-in-node=\"0\"\u003ePeptic Ulcer Bleeding Protocol:\u003c\/b\u003e Typically administered as an initial 80mg bolus infusion followed by a continuous infusion or intermittent 40mg doses as directed by the attending gastroenterologist\/intensivist.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"18,2,0\"\u003e\u003cb data-path-to-node=\"18,2,0\" data-index-in-node=\"0\"\u003eProfessional Healthcare Use:\u003c\/b\u003e Must be administered exclusively by a qualified healthcare professional in a clinic, hospital, or critical care setting.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ol\u003e\r\\n\u003ch3 data-path-to-node=\"19\"\u003ePrecautions\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"20\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,0,0\"\u003e\u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"0\"\u003ePrescription-Only Parenteral:\u003c\/b\u003e Strictly for professional healthcare administration; do not self-administer.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,1,0\"\u003eAvoid rapid IV push; ensure administration speed strictly follows clinical guidelines to prevent local vascular irritation.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,2,0\"\u003eDiagnostic evaluation is recommended prior to initiation to rule out gastric malignancy, as PPI therapy can mask warning symptoms (e.g., unintended weight loss, persistent vomiting, dysphagia, hematemesis).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,3,0\"\u003eAdjust dosage in patients with severe hepatic impairment (maximum recommended daily IV dose is 20mg).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,4,0\"\u003eConsult an attending physician prior to use during pregnancy or lactation.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,5,0\"\u003eKeep out of reach of children.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"21\"\u003eStorage Instructions\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"22\"\u003eStore the un-reconstituted dry powder vial in a cool, dry place below 30°C, protected from direct light and heat. Reconstituted solutions should be used immediately or within 4 hours if kept below 25°C. Protect reconstituted solution from light. Do not freeze.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"23\"\u003eManufacturer Information\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"24\"\u003eFormulated and manufactured in strict compliance with international pharmaceutical quality standards, dedicated to engineering advanced gastroenterology and critical care parenteral therapies that restore mucosal integrity and improve patient outcomes.\u003c\/p\u003e\r\\n\r\\n\u003c\/div\u003e\r\\n\u003c\/div\u003e\r\\n\u003ch4\u003e\u003c\/h4\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":44164488986683,"sku":null,"price":362.73,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0695\/4899\/8715\/files\/PROMIZ-40-INJ.jpg?v=1789027877","url":"https:\/\/pharmaservicesgroup.com\/products\/promiz-injection-40mg-intravenous-omeprazole-acid-suppression-therapy","provider":"Pharma Services Distribution","version":"1.0","type":"link"}