{"product_id":"nalbusol-injection-10mg-20mg-parenteral-opioid-agonist-antagonist-analgesic","title":"Nalbusol Injection (10mg \u0026 20mg) - Parenteral Opioid Agonist-Antagonist Analgesic","description":"\u003cdiv class=\"container\"\u003e\r\\n\u003cdiv id=\"model-response-message-contentr_752ff3f55d1327a7\" class=\"markdown markdown-main-panel md-content enable-luminous-fast-follows enable-updated-hr-color tutor-markdown-rendering\" dir=\"ltr\" aria-busy=\"false\" aria-live=\"polite\"\u003e\r\\n\u003ch2 data-path-to-node=\"11\"\u003eProduct Overview\u003c\/h2\u003e\r\\n\u003cp data-path-to-node=\"12\"\u003e\u003cb data-path-to-node=\"12\" data-index-in-node=\"0\"\u003eNalbusol Injection\u003c\/b\u003e is a potent, synthetic parenteral opioid analgesic containing \u003cb data-path-to-node=\"12\" data-index-in-node=\"81\"\u003eNalbuphine Hydrochloride\u003c\/b\u003e. Engineered for Intravenous (IV), Intramuscular (IM), or Subcutaneous (SC) administration, Nalbusol provides rapid, effective relief from moderate-to-severe pain. It is widely indicated for obstetrical analgesia during labor and delivery, pre- and post-operative pain management, and as an adjunct to balanced anesthesia. Featuring a unique mixed agonist-antagonist profile, Nalbusol offers powerful analgesic efficacy with a ceiling effect on respiratory depression, providing an enhanced safety margin compared to classic pure \u003cspan class=\"math-inline\" data-math=\"\\mu\" data-index-in-node=\"635\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord mathnormal\"\u003eμ\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e-opioid agonists.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"13\"\u003eKey Benefits\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"14\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,0,0\"\u003e\u003cb data-path-to-node=\"14,0,0\" data-index-in-node=\"0\"\u003eRapid Systemic Analgesia:\u003c\/b\u003e Delivers swift pain relief within minutes of administration, crucial for acute surgical and obstetric scenarios.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,1,0\"\u003e\u003cb data-path-to-node=\"14,1,0\" data-index-in-node=\"0\"\u003eCeiling Effect on Respiratory Depression:\u003c\/b\u003e Unlike pure mu-opioids, higher doses do not proportionately increase respiratory depression, enhancing patient safety.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,2,0\"\u003e\u003cb data-path-to-node=\"14,2,0\" data-index-in-node=\"0\"\u003eEffective Obstetric Analgesia:\u003c\/b\u003e Provides excellent labor pain relief with minimal duration of neonatal respiratory impact when monitored correctly.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,3,0\"\u003e\u003cb data-path-to-node=\"14,3,0\" data-index-in-node=\"0\"\u003eLow Hemodynamic Impact:\u003c\/b\u003e Maintains cardiovascular stability with minimal effect on blood pressure and heart rate during surgical procedures.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,4,0\"\u003e\u003cb data-path-to-node=\"14,4,0\" data-index-in-node=\"0\"\u003eReduced Abuse Potential:\u003c\/b\u003e Possesses lower dependence and abuse potential compared to pure schedule-II opioids due to its kappa-agonist \/ mu-antagonist action.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"15\"\u003eHow It Works\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"16\"\u003eNalbusol Injection (Nalbuphine HCl) functions as a \u003cb data-path-to-node=\"16\" data-index-in-node=\"51\"\u003emixed opioid agonist-antagonist\u003c\/b\u003e. It acts as a potent \u003cb data-path-to-node=\"16\" data-index-in-node=\"104\"\u003ekappa (\u003cspan class=\"math-inline\" data-math=\"\\kappa\" data-index-in-node=\"111\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord mathnormal\"\u003eκ\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e) opioid receptor agonist\u003c\/b\u003e and a \u003cb data-path-to-node=\"16\" data-index-in-node=\"149\"\u003ecompetitive mu (\u003cspan class=\"math-inline\" data-math=\"\\mu\" data-index-in-node=\"165\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord mathnormal\"\u003eμ\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e) opioid receptor partial agonist\/antagonist\u003c\/b\u003e. Activation of \u003cspan class=\"math-inline\" data-math=\"\\kappa\" data-index-in-node=\"228\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord mathnormal\"\u003eκ\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e-receptors in the spinal cord and brain mediates powerful analgesia and sedation without inducing profound \u003cspan class=\"math-inline\" data-math=\"\\mu\" data-index-in-node=\"341\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord mathnormal\"\u003eμ\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e-mediated respiratory depression or euphoria. Simultaneously, its \u003cspan class=\"math-inline\" data-math=\"\\mu\" data-index-in-node=\"410\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord mathnormal\"\u003eμ\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e-antagonist activity decreases the risk of pure \u003cspan class=\"math-inline\" data-math=\"\\mu\" data-index-in-node=\"461\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord mathnormal\"\u003eμ\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e-agonist side effects and can partially reverse or precipitate withdrawal in opioid-dependent individuals.\u003c\/p\u003e\r\\n\r\\n\u003ch2 data-path-to-node=\"18\"\u003eWooCommerce Attribute \/ Variation Details\u003c\/h2\u003e\r\\n\u003ch3 data-path-to-node=\"19\"\u003eVariation 1: NALBUSOL INJECTION 10MG (10mg\/1ml)\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"20\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,0,0\"\u003e\u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"0\"\u003eSKU:\u003c\/b\u003e \u003ccode data-path-to-node=\"20,0,0\" data-index-in-node=\"5\"\u003eNAL-INJ-10\u003c\/code\u003e\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,1,0\"\u003e\u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"0\"\u003eShort Description:\u003c\/b\u003e Ideal for moderate pain control, pediatric analgesia, lighter post-operative discomfort, and initial titration in sensitive patients.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,2,0\"\u003e\u003cb data-path-to-node=\"20,2,0\" data-index-in-node=\"0\"\u003eKey Active Ingredient:\u003c\/b\u003e Nalbuphine Hydrochloride — 10mg per 1ml ampoule.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,3,0\"\u003e\u003cb data-path-to-node=\"20,3,0\" data-index-in-node=\"0\"\u003eTarget Indications:\u003c\/b\u003e Moderate post-operative pain, obstetrical analgesia during early labor, pre-anesthetic sedation, and minor surgical procedures.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,4,0\"\u003e\u003cb data-path-to-node=\"20,4,0\" data-index-in-node=\"0\"\u003eStandard Dosing:\u003c\/b\u003e 10mg administered via IV, IM, or SC every 3 to 6 hours as needed (adjusted by an attending physician based on weight and severity).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"21\"\u003eVariation 2: NALBUSOL INJECTION 20MG (20mg\/2ml)\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"22\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003eSKU:\u003c\/b\u003e \u003ccode data-path-to-node=\"22,0,0\" data-index-in-node=\"5\"\u003eNAL-INJ-20\u003c\/code\u003e\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eShort Description:\u003c\/b\u003e High-strength formulation designed for severe acute pain, major surgical procedures, trauma analgesia, and anesthesia supplementation.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eKey Active Ingredient:\u003c\/b\u003e Nalbuphine Hydrochloride — 20mg per ampoule.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,3,0\"\u003e\u003cb data-path-to-node=\"22,3,0\" data-index-in-node=\"0\"\u003eTarget Indications:\u003c\/b\u003e Severe post-operative pain, major visceral pain, emergency trauma analgesia, and as an adjunct to balanced general anesthesia.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,4,0\"\u003e\u003cb data-path-to-node=\"22,4,0\" data-index-in-node=\"0\"\u003eStandard Dosing:\u003c\/b\u003e 20mg administered via IV, IM, or SC every 3 to 6 hours as needed; maximum recommended single dose is 20mg (up to 160mg daily total).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch2 data-path-to-node=\"24\"\u003eGeneral Product Details (Shared across variations)\u003c\/h2\u003e\r\\n\u003ch3 data-path-to-node=\"25\"\u003eKey Active Ingredients\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"26\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"26,0,0\"\u003e\u003cb data-path-to-node=\"26,0,0\" data-index-in-node=\"0\"\u003eNalbuphine Hydrochloride (10mg \/ 20mg per ampoule):\u003c\/b\u003e Phenanthrene derivative mixed opioid agonist-antagonist that provides central analgesic action while limiting respiratory depression.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"27\"\u003eDirections for Use\u003c\/h3\u003e\r\\n\u003col start=\"1\" data-path-to-node=\"28\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"28,0,0\"\u003e\u003cb data-path-to-node=\"28,0,0\" data-index-in-node=\"0\"\u003eAdministration Routes:\u003c\/b\u003e Suitable for Intravenous (IV), Intramuscular (IM), or Subcutaneous (SC) administration.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"28,1,0\"\u003e\u003cb data-path-to-node=\"28,1,0\" data-index-in-node=\"0\"\u003eIV Administration:\u003c\/b\u003e Inject slowly over 3 to 5 minutes to minimize transient side effects such as nausea or dizziness.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"28,2,0\"\u003e\u003cb data-path-to-node=\"28,2,0\" data-index-in-node=\"0\"\u003eClinical Dosing:\u003c\/b\u003e Must be individually titrated according to pain severity, physical status, and concurrent medications under direct medical supervision.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"28,3,0\"\u003e\u003cb data-path-to-node=\"28,3,0\" data-index-in-node=\"0\"\u003eProfessional Healthcare Use:\u003c\/b\u003e Must be administered exclusively by qualified healthcare professionals in hospital, surgical, or clinical emergency settings.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ol\u003e\r\\n\u003ch3 data-path-to-node=\"29\"\u003ePrecautions\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"30\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,0,0\"\u003e\u003cb data-path-to-node=\"30,0,0\" data-index-in-node=\"0\"\u003eControlled Parenteral Agent:\u003c\/b\u003e Strictly for professional medical and hospital administration; do not self-administer.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,1,0\"\u003e\u003cb data-path-to-node=\"30,1,0\" data-index-in-node=\"0\"\u003eOpioid Dependence Risk:\u003c\/b\u003e May precipitate acute withdrawal symptoms if administered to patients physically dependent on pure \u003cspan class=\"math-inline\" data-math=\"\\mu\" data-index-in-node=\"123\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord mathnormal\"\u003eμ\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e-opioid agonists (e.g., morphine, fentanyl, methadone).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,2,0\"\u003e\u003cb data-path-to-node=\"30,2,0\" data-index-in-node=\"0\"\u003eHead Injury \u0026amp; Increased Intracranial Pressure:\u003c\/b\u003e Exercise extreme caution in patients with head injuries or pre-existing elevated intracranial pressure.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,3,0\"\u003e\u003cb data-path-to-node=\"30,3,0\" data-index-in-node=\"0\"\u003eHepatic \u0026amp; Renal Impairment:\u003c\/b\u003e Reduce dosage and monitor closely in patients with impaired liver or kidney function.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,4,0\"\u003eCauses sedation, somnolence, and dizziness; patients must not drive or operate machinery post-administration.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,5,0\"\u003eConsult an attending physician before use during pregnancy or lactation.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"30,6,0\"\u003eKeep out of reach of children.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"31\"\u003eStorage Instructions\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"32\"\u003eStore in a cool, dry place below 30°C. Protect from direct light, excessive heat, and freezing. Retain ampoules in their original carton until ready for immediate sterile use. Discard any unused portion.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"33\"\u003eManufacturer Information\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"34\"\u003eFormulated and manufactured in strict compliance with international pharmaceutical quality standards, dedicated to providing high-efficacy parenteral analgesics and critical care solutions that optimize patient comfort and clinical safety.\u003c\/p\u003e\r\\n\r\\n\u003c\/div\u003e\r\\n\u003c\/div\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":44164488724539,"sku":null,"price":0.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0695\/4899\/8715\/files\/images.png?v=1789027872","url":"https:\/\/pharmaservicesgroup.com\/products\/nalbusol-injection-10mg-20mg-parenteral-opioid-agonist-antagonist-analgesic","provider":"Pharma Services Distribution","version":"1.0","type":"link"}