{"product_id":"migxen-85-500mg-tablets-targeted-combination-acute-migraine-relief","title":"Migxen 85\/500mg Tablets - Targeted Combination Acute Migraine Relief","description":"\u003cdiv class=\"container\"\u003e\r\\n\u003cdiv id=\"model-response-message-contentr_ed6b23d2d13ccf3d\" class=\"markdown markdown-main-panel md-content enable-luminous-fast-follows enable-updated-hr-color tutor-markdown-rendering\" dir=\"ltr\" aria-busy=\"false\" aria-live=\"polite\"\u003e\r\\n\u003ch2 data-path-to-node=\"9\"\u003eProduct Overview\u003c\/h2\u003e\r\\n\u003cp data-path-to-node=\"10\"\u003e\u003cb data-path-to-node=\"10\" data-index-in-node=\"0\"\u003eMigxen 85\/500mg Tablets\u003c\/b\u003e are an advanced fixed-dose combination antimigraine therapy combining \u003cb data-path-to-node=\"10\" data-index-in-node=\"94\"\u003eSumatriptan Succinate (85mg)\u003c\/b\u003e and \u003cb data-path-to-node=\"10\" data-index-in-node=\"127\"\u003eNaproxen Sodium (500mg)\u003c\/b\u003e. Engineered specifically for the acute treatment of migraine attacks with or without aura in adults, Migxen addresses both the neurovascular cause and the inflammatory cascade of migraines. By combining a targeted 5-HT1B\/1D receptor agonist (triptan) with a fast-acting nonsteroidal anti-inflammatory drug (NSAID), Migxen provides superior, longer-lasting relief from throbbing headache pain, photophobia (light sensitivity), phonophobia (sound sensitivity), and associated nausea compared to single-agent therapies.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"11\"\u003eKey Benefits\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"12\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,0,0\"\u003e\u003cb data-path-to-node=\"12,0,0\" data-index-in-node=\"0\"\u003eDual-Mechanism Synergism:\u003c\/b\u003e Delivers enhanced, long-lasting pain relief by targeting both neurogenic inflammation and cranial vasodilation simultaneously.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,1,0\"\u003e\u003cb data-path-to-node=\"12,1,0\" data-index-in-node=\"0\"\u003eReduces Migraine Recurrence:\u003c\/b\u003e Combining Naproxen Sodium with Sumatriptan significantly lowers the rate of 24-hour migraine recurrence compared to triptan monotherapy.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,2,0\"\u003e\u003cb data-path-to-node=\"12,2,0\" data-index-in-node=\"0\"\u003eComprehensive Symptom Control:\u003c\/b\u003e Effectively alleviates severe head pain, nausea, vomiting, photophobia, and phonophobia.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,3,0\"\u003e\u003cb data-path-to-node=\"12,3,0\" data-index-in-node=\"0\"\u003eRapid Onset of Action:\u003c\/b\u003e Fast-dissolving formulation provides measurable pain relief within 30 to 60 minutes of ingestion.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"12,4,0\"\u003e\u003cb data-path-to-node=\"12,4,0\" data-index-in-node=\"0\"\u003eSingle-Tablet Convenience:\u003c\/b\u003e Eliminates the need to take separate triptan and NSAID doses during an acute migraine attack.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"13\"\u003eHow It Works\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"14\"\u003eMigxen 85\/500mg Tablets function via two distinct, complementary pathways:\u003c\/p\u003e\r\\n\r\\n\u003col start=\"1\" data-path-to-node=\"15\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"15,0,0\"\u003e\u003cb data-path-to-node=\"15,0,0\" data-index-in-node=\"0\"\u003eSumatriptan (85mg):\u003c\/b\u003e Selective \u003cb data-path-to-node=\"15,0,0\" data-index-in-node=\"30\"\u003eserotonin \u003cspan class=\"math-inline\" data-math=\"5\\text{-HT}_{1\\text{B}\/1\\text{D}}\" data-index-in-node=\"40\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord\"\u003e5\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord text\"\u003e-HT\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t vlist-t2\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mord mtight\"\u003e1\u003cspan class=\"mord text mtight\"\u003eB\u003c\/span\u003e\/1\u003cspan class=\"mord text mtight\"\u003eD\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-s\"\u003e​\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e receptor agonist\u003c\/b\u003e. It binds to receptors on intracranial blood vessels and sensory nerve endings of the trigeminal system. This induces cranial vasoconstriction, suppresses trigeminal nerve activation, and inhibits the release of vasoactive pro-inflammatory neuropeptides (such as CGRP).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"15,1,0\"\u003e\u003cb data-path-to-node=\"15,1,0\" data-index-in-node=\"0\"\u003eNaproxen Sodium (500mg):\u003c\/b\u003e Non-selective \u003cb data-path-to-node=\"15,1,0\" data-index-in-node=\"39\"\u003ecyclooxygenase (COX-1 and COX-2) inhibitor\u003c\/b\u003e. It inhibits the enzymatic synthesis of prostaglandins, preventing neurogenic inflammatory sensitization in central and peripheral pain pathways and halting sustained pain transmission.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ol\u003e\r\\n\u003ch3 data-path-to-node=\"16\"\u003eKey Active Ingredients\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"17\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"17,0,0\"\u003e\u003cb data-path-to-node=\"17,0,0\" data-index-in-node=\"0\"\u003eSumatriptan Succinate (equivalent to 85mg Sumatriptan):\u003c\/b\u003e Vascular serotonin agonist that constricts swollen cranial vessels and inhibits neurogenic inflammatory peptide release.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"17,1,0\"\u003e\u003cb data-path-to-node=\"17,1,0\" data-index-in-node=\"0\"\u003eNaproxen Sodium (500mg):\u003c\/b\u003e Long-acting NSAID that inhibits prostaglandin synthesis to eliminate neurogenic tissue inflammation and prolonged headache pain.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"18\"\u003eDirections for Use\u003c\/h3\u003e\r\\n\u003col start=\"1\" data-path-to-node=\"19\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"19,0,0\"\u003e\u003cb data-path-to-node=\"19,0,0\" data-index-in-node=\"0\"\u003eAdministration:\u003c\/b\u003e Swallow 1 film-coated tablet whole with a full glass of water at the very first sign of a migraine attack. Do not crush, split, or chew the tablet.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"19,1,0\"\u003e\u003cb data-path-to-node=\"19,1,0\" data-index-in-node=\"0\"\u003eDosing:\u003c\/b\u003e\u003c\/p\u003e\r\\n\r\\n\u003cul data-path-to-node=\"19,1,1\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"19,1,1,0,0\"\u003e\u003cb data-path-to-node=\"19,1,1,0,0\" data-index-in-node=\"0\"\u003eAdults (18 years and older):\u003c\/b\u003e 1 tablet per acute migraine attack.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"19,1,1,1,0\"\u003e\u003cb data-path-to-node=\"19,1,1,1,0\" data-index-in-node=\"0\"\u003eSecond Dose:\u003c\/b\u003e If the migraine returns or response is incomplete, a second dose may be taken \u003cb data-path-to-node=\"19,1,1,1,0\" data-index-in-node=\"91\"\u003eat least 2 hours apart\u003c\/b\u003e.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"19,1,1,2,0\"\u003e\u003cb data-path-to-node=\"19,1,1,2,0\" data-index-in-node=\"0\"\u003eMaximum Dose:\u003c\/b\u003e Do not exceed \u003cb data-path-to-node=\"19,1,1,2,0\" data-index-in-node=\"28\"\u003e2 tablets in any 24-hour period\u003c\/b\u003e.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"19,2,0\"\u003e\u003cb data-path-to-node=\"19,2,0\" data-index-in-node=\"0\"\u003eImportant Note:\u003c\/b\u003e Not intended for prophylactic (preventative) treatment of migraines or for the management of hemiplegic or basilar migraines.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ol\u003e\r\\n\u003ch3 data-path-to-node=\"20\"\u003ePrecautions\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"21\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"21,0,0\"\u003e\u003cb data-path-to-node=\"21,0,0\" data-index-in-node=\"0\"\u003ePrescription-Only Medication:\u003c\/b\u003e Take strictly as prescribed by a healthcare provider.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"21,1,0\"\u003e\u003cb data-path-to-node=\"21,1,0\" data-index-in-node=\"0\"\u003eCardiovascular \u0026amp; Cerebrovascular Warning:\u003c\/b\u003e Contraindicated in patients with ischemic heart disease (e.g., angina, prior myocardial infarction), uncontrolled hypertension, coronary artery vasospasm (Prinzmetal’s angina), peripheral vascular disease, or history of stroke\/TIA.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"21,2,0\"\u003e\u003cb data-path-to-node=\"21,2,0\" data-index-in-node=\"0\"\u003eGastrointestinal Risk:\u003c\/b\u003e Contains Naproxen Sodium; use with caution in patients with a history of peptic ulcer disease or GI bleeding.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"21,3,0\"\u003e\u003cb data-path-to-node=\"21,3,0\" data-index-in-node=\"0\"\u003eSerotonin Syndrome Risk:\u003c\/b\u003e Exercise caution when co-administered with SSRIs, SNRIs, or other serotonergic medications. Contraindicated within 14 days of MAO inhibitor therapy.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"21,4,0\"\u003e\u003cb data-path-to-node=\"21,4,0\" data-index-in-node=\"0\"\u003eRenal \u0026amp; Hepatic Impairment:\u003c\/b\u003e Avoid use in severe hepatic impairment or severe renal insufficiency (\u003cspan class=\"math-inline\" data-math=\"CL_{cr} \u0026lt; 30\\text{ ml\/min}\" data-index-in-node=\"98\"\u003e\u003cspan class=\"katex\"\u003e\u003cspan class=\"katex-html\" aria-hidden=\"true\"\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord mathnormal\"\u003eC\u003c\/span\u003e\u003cspan class=\"mord\"\u003e\u003cspan class=\"mord mathnormal\"\u003eL\u003c\/span\u003e\u003cspan class=\"msupsub\"\u003e\u003cspan class=\"vlist-t vlist-t2\"\u003e\u003cspan class=\"vlist-r\"\u003e\u003cspan class=\"vlist\"\u003e\u003cspan class=\"\"\u003e\u003cspan class=\"sizing reset-size6 size3 mtight\"\u003e\u003cspan class=\"mord mtight\"\u003e\u003cspan class=\"mord mathnormal mtight\"\u003ecr\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"vlist-s\"\u003e​\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"mrel\"\u003e\u0026lt;\u003c\/span\u003e\u003c\/span\u003e\u003cspan class=\"base\"\u003e\u003cspan class=\"mord\"\u003e30\u003c\/span\u003e\u003cspan class=\"mord text\"\u003e\u003cspan class=\"mord\"\u003e ml\/min\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e\u003c\/span\u003e).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"21,5,0\"\u003eConsult a physician before use during pregnancy or lactation (specifically avoid during late pregnancy due to early closure of the ductus arteriosus).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"21,6,0\"\u003eKeep out of reach of children.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"22\"\u003eStorage Instructions\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"23\"\u003eStore in a cool, dry place below 30°C, protected from direct light, heat, and moisture. Keep tablets sealed in their original blister package until time of administration.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"24\"\u003eManufacturer Information\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"25\"\u003eFormulated and manufactured in strict compliance with international pharmaceutical quality standards, dedicated to providing advanced neurology and pain management therapies that restore quality of life and deliver fast, sustained relief.\u003c\/p\u003e\r\\n\r\\n\u003c\/div\u003e\r\\n\u003c\/div\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":44164566843451,"sku":null,"price":270.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0695\/4899\/8715\/files\/MIGEXN.jpg?v=1789028652","url":"https:\/\/pharmaservicesgroup.com\/products\/migxen-85-500mg-tablets-targeted-combination-acute-migraine-relief","provider":"Pharma Services Distribution","version":"1.0","type":"link"}