{"product_id":"m-floxsel-infusion-400mg-250ml-intravenous-fluoroquinolone-antibacterial-solution","title":"M-Floxsel Infusion 400mg\/250ml - Intravenous Fluoroquinolone Antibacterial Solution","description":"\u003cdiv class=\"container\"\u003e\r\\n\u003cdiv id=\"model-response-message-contentr_241c6a63d00f0183\" class=\"markdown markdown-main-panel md-content enable-luminous-fast-follows enable-updated-hr-color tutor-markdown-rendering\" dir=\"ltr\" aria-busy=\"false\" aria-live=\"polite\"\u003e\r\\n\u003ch2 data-path-to-node=\"11\"\u003eProduct Overview\u003c\/h2\u003e\r\\n\u003cp data-path-to-node=\"12\"\u003e\u003cb data-path-to-node=\"12\" data-index-in-node=\"0\"\u003eM-Floxsel Infusion 400mg\/250ml\u003c\/b\u003e is a high-potency, ready-to-use parenteral fourth-generation fluoroquinolone formulation containing \u003cb data-path-to-node=\"12\" data-index-in-node=\"131\"\u003eMoxifloxacin Hydrochloride (400mg in 250ml saline\/aqueous solution)\u003c\/b\u003e. Formulated for Intravenous (IV) infusion, M-Floxsel Infusion provides immediate systemic bioavailability for hospitalized or critically ill patients unable to tolerate oral administration. It is indicated for severe community-acquired pneumonia (CAP), complicated skin and skin structure infections (cSSSI), complicated intra-abdominal infections (cIAI), and acute severe exacerbations of chronic bronchitis caused by multi-drug resistant bacterial pathogens.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"13\"\u003eKey Benefits\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"14\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,0,0\"\u003e\u003cb data-path-to-node=\"14,0,0\" data-index-in-node=\"0\"\u003eImmediate Systemic Availability:\u003c\/b\u003e Provides rapid 100% systemic bioequivalent drug concentrations required for inpatient critical care settings.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,1,0\"\u003e\u003cb data-path-to-node=\"14,1,0\" data-index-in-node=\"0\"\u003eBroad-Spectrum Bactericidal Coverage:\u003c\/b\u003e Active against resistant Gram-positive pathogens (including penicillin-resistant \u003ci data-path-to-node=\"14,1,0\" data-index-in-node=\"119\"\u003eStreptococcus pneumoniae\u003c\/i\u003e), Gram-negative bacilli, atypicals, and anaerobic isolates.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,2,0\"\u003e\u003cb data-path-to-node=\"14,2,0\" data-index-in-node=\"0\"\u003eReady-to-Use Premixed Solution:\u003c\/b\u003e Supplied in a pre-formulated 250ml infusion bottle\/bag, reducing preparation time and contamination risk in clinical environments.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,3,0\"\u003e\u003cb data-path-to-node=\"14,3,0\" data-index-in-node=\"0\"\u003eTargeted Respiratory \u0026amp; Tissue Penetration:\u003c\/b\u003e Demonstrates high concentration ratios in lung tissue, alveolar macrophages, bronchial mucosa, and skin structures.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,4,0\"\u003e\u003cb data-path-to-node=\"14,4,0\" data-index-in-node=\"0\"\u003eSmooth Step-Down Therapy:\u003c\/b\u003e Enables seamless transition to oral M-Floxsel 400mg tablets once the patient stabilizes clinically.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"15\"\u003eHow It Works\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"16\"\u003eM-Floxsel Infusion 400mg\/250ml (Moxifloxacin) exerts rapid bactericidal action by concurrently inhibiting two essential bacterial enzymes necessary for chromosome replication and cell division: \u003cb data-path-to-node=\"16\" data-index-in-node=\"194\"\u003eDNA gyrase (topoisomerase II)\u003c\/b\u003e and \u003cb data-path-to-node=\"16\" data-index-in-node=\"228\"\u003etopoisomerase IV\u003c\/b\u003e. By binding to these targets during bacterial DNA transcription and replication, M-Floxsel induces double-stranded DNA cleavage, prevents repair mechanisms, and triggers rapid microbial cell lysis.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"17\"\u003eKey Active Ingredients\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"18\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"18,0,0\"\u003e\u003cb data-path-to-node=\"18,0,0\" data-index-in-node=\"0\"\u003eMoxifloxacin Hydrochloride (400mg per 250ml solution):\u003c\/b\u003e Synthetic 8-methoxyfluoroquinolone antibacterial agent in an isotonic aqueous vehicle for intravenous administration.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"19\"\u003eDirections for Use\u003c\/h3\u003e\r\\n\u003col start=\"1\" data-path-to-node=\"20\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,0,0\"\u003e\u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"0\"\u003eAdministration Route:\u003c\/b\u003e Strictly for \u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"35\"\u003eIntravenous (IV) Infusion\u003c\/b\u003e. Do not administer via intramuscular, subcutaneous, or rapid bolus injection.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,1,0\"\u003e\u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"0\"\u003eInfusion Rate:\u003c\/b\u003e Administer the 250ml premixed solution as a slow intravenous infusion over a period of \u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"102\"\u003e60 minutes\u003c\/b\u003e.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,2,0\"\u003e\u003cb data-path-to-node=\"20,2,0\" data-index-in-node=\"0\"\u003eDosing Schedule:\u003c\/b\u003e Typically 400mg (250ml) administered \u003cb data-path-to-node=\"20,2,0\" data-index-in-node=\"54\"\u003eonce every 24 hours\u003c\/b\u003e as determined by an attending infectious disease specialist or clinical physician.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,3,0\"\u003e\u003cb data-path-to-node=\"20,3,0\" data-index-in-node=\"0\"\u003eProfessional Healthcare Use:\u003c\/b\u003e Must be administered exclusively by qualified medical personnel in a hospital, clinic, or emergency department.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ol\u003e\r\\n\u003ch3 data-path-to-node=\"21\"\u003ePrecautions\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"22\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003ePrescription-Only Parenteral:\u003c\/b\u003e For clinical and inpatient hospital administration only; strictly prohibited for self-administration.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eSerious Fluoroquinolone Warnings:\u003c\/b\u003e Associated with severe risks including tendonitis, tendon rupture, peripheral neuropathy, central nervous system toxicity, and aortic aneurysm\/dissection. Discontinue at the first sign of tendon pain or neurological disturbance.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eQT Prolongation:\u003c\/b\u003e Avoid in patients with known prolongation of the QTc interval, uncorrected hypokalemia, or co-administration with Class IA\/Class III antiarrhythmics.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,3,0\"\u003e\u003cb data-path-to-node=\"22,3,0\" data-index-in-node=\"0\"\u003eInfusion Site Care:\u003c\/b\u003e Administer slowly over 60 minutes to minimize venous irritation, phlebitis, and local pain.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,4,0\"\u003eConsult an attending physician prior to use during pregnancy or lactation.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,5,0\"\u003eKeep out of reach of children.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"23\"\u003eStorage Instructions\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"24\"\u003eStore in a cool, dry place below 30°C. Protect from direct sunlight, excessive heat, and freezing. Retain in original protective packaging until administration; inspect for clarity and absence of particulate matter prior to use.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"25\"\u003eManufacturer Information\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"26\"\u003eFormulated and manufactured in strict compliance with international pharmaceutical quality standards, committed to advancing parenteral anti-infective therapies that effectively combat antimicrobial resistance and support critical inpatient recovery.\u003c\/p\u003e\r\\n\r\\n\u003c\/div\u003e\r\\n\u003c\/div\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":44164488626235,"sku":null,"price":581.7,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0695\/4899\/8715\/files\/M-FLOXSEL-INF.jpg?v=1789027871","url":"https:\/\/pharmaservicesgroup.com\/products\/m-floxsel-infusion-400mg-250ml-intravenous-fluoroquinolone-antibacterial-solution","provider":"Pharma Services Distribution","version":"1.0","type":"link"}