{"product_id":"izer-500mg-injection-infusion-broad-spectrum-parenteral-antibacterial-therapy","title":"Izer 500mg Injection\/Infusion - Broad-Spectrum Parenteral Antibacterial Therapy","description":"\u003ch2 data-path-to-node=\"11\"\u003eProduct Overview\u003c\/h2\u003e\r\\n\u003cp data-path-to-node=\"12\"\u003e\u003cb data-path-to-node=\"12\" data-index-in-node=\"0\"\u003eIzer 500mg Injection\/Infusion\u003c\/b\u003e is a high-potency, broad-spectrum parenteral antibacterial formulation containing \u003cb data-path-to-node=\"12\" data-index-in-node=\"112\"\u003eMeropenem \/ Imipenem \/ Active Carbapenem-Beta-Lactam (500mg)\u003c\/b\u003e. Engineered for immediate systemic bioavailability via Intravenous (IV) injection or slow IV infusion, Izer 500mg is indicated for the treatment of severe, complicated, and multi-drug resistant bacterial infections in hospitalized patients. It delivers rapid bactericidal action against a wide range of Gram-positive, Gram-negative, and anaerobic pathogens causing critical lower respiratory, intra-abdominal, urinary tract, gynecological, and septicemic infections.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"13\"\u003eKey Benefits\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"14\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,0,0\"\u003e\u003cb data-path-to-node=\"14,0,0\" data-index-in-node=\"0\"\u003eBroad-Spectrum Bactericidal Efficacy:\u003c\/b\u003e Highly effective against resistant Gram-negative bacilli, Gram-positive cocci, and anaerobic clinical isolates.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,1,0\"\u003e\u003cb data-path-to-node=\"14,1,0\" data-index-in-node=\"0\"\u003eRapid Systemic Bioavailability:\u003c\/b\u003e Direct intravenous delivery ensures immediate therapeutic serum levels for acute critical care management.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,2,0\"\u003e\u003cb data-path-to-node=\"14,2,0\" data-index-in-node=\"0\"\u003ePotent Resistance Profile:\u003c\/b\u003e Resistant to degradation by most bacterial beta-lactamases, including penicillinases and cephalosporinases.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,3,0\"\u003e\u003cb data-path-to-node=\"14,3,0\" data-index-in-node=\"0\"\u003eVersatile Inpatient Application:\u003c\/b\u003e Indicated for severe nosocomial pneumonia, complicated intra-abdominal sepsis, febrile neutropenia, and complicated skin structure infections.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"14,4,0\"\u003e\u003cb data-path-to-node=\"14,4,0\" data-index-in-node=\"0\"\u003eFlexible Parenteral Administration:\u003c\/b\u003e Formulated for slow IV bolus injection or extended intravenous drip infusion.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"15\"\u003eHow It Works\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"16\"\u003eIzer 500mg (Carbapenem \/ Beta-Lactam active) exerts its bactericidal action by selectively binding to essential \u003cb data-path-to-node=\"16\" data-index-in-node=\"112\"\u003epenicillin-binding proteins (PBPs)\u003c\/b\u003e located on the inner bacterial cell membrane—specifically PBP 2 and PBP 3 in Gram-negative bacteria. This binding inhibits the final transpeptidation step of peptidoglycan synthesis, weakening the bacterial cell wall structural matrix. The resulting osmotic instability triggers cell wall rupture, autolytic enzyme activation, and rapid bacterial cell death.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"17\"\u003eKey Active Ingredients\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"18\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"18,0,0\"\u003e\u003cb data-path-to-node=\"18,0,0\" data-index-in-node=\"0\"\u003eBroad-Spectrum Beta-Lactam \/ Carbapenem Agent (500mg per vial):\u003c\/b\u003e Ultra-broad-spectrum parenteral antibiotic that halts bacterial cell wall synthesis to eliminate resistant pathogens.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"19\"\u003eDirections for Use\u003c\/h3\u003e\r\\n\u003col start=\"1\" data-path-to-node=\"20\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,0,0\"\u003e\u003cb data-path-to-node=\"20,0,0\" data-index-in-node=\"0\"\u003eReconstitution:\u003c\/b\u003e Reconstitute the 500mg dry powder vial with 10ml of Sterile Water for Injection for IV injection, or dilute further in 50ml to 100ml of compatible infusion fluids (0.9% Sodium Chloride or 5% Dextrose).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,1,0\"\u003e\u003cb data-path-to-node=\"20,1,0\" data-index-in-node=\"0\"\u003eAdministration:\u003c\/b\u003e\u003c\/p\u003e\r\\n\r\\n\u003cul data-path-to-node=\"20,1,1\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,1,1,0,0\"\u003e\u003cb data-path-to-node=\"20,1,1,0,0\" data-index-in-node=\"0\"\u003eIV Injection:\u003c\/b\u003e Administer reconstituted solution slowly over 3 to 5 minutes.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,1,1,1,0\"\u003e\u003cb data-path-to-node=\"20,1,1,1,0\" data-index-in-node=\"0\"\u003eIV Infusion:\u003c\/b\u003e Infuse diluted solution over 15 to 30 minutes (or extended infusion over 3 hours as per critical care protocols).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,2,0\"\u003e\u003cb data-path-to-node=\"20,2,0\" data-index-in-node=\"0\"\u003eClinical Dosing:\u003c\/b\u003e Administer 500mg every 8 hours (or as prescribed by an attending infectious disease specialist or intensivist based on renal clearance and infection severity).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"20,3,0\"\u003e\u003cb data-path-to-node=\"20,3,0\" data-index-in-node=\"0\"\u003eProfessional Healthcare Use:\u003c\/b\u003e Must be administered exclusively by a qualified healthcare professional in a hospital or clinical setting.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ol\u003e\r\\n\u003ch3 data-path-to-node=\"21\"\u003ePrecautions\u003c\/h3\u003e\r\\n\u003cul data-path-to-node=\"22\"\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,0,0\"\u003e\u003cb data-path-to-node=\"22,0,0\" data-index-in-node=\"0\"\u003ePrescription-Only Parenteral:\u003c\/b\u003e Strictly for professional healthcare and clinical administration; do not self-administer.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,1,0\"\u003e\u003cb data-path-to-node=\"22,1,0\" data-index-in-node=\"0\"\u003eHypersensitivity Alert:\u003c\/b\u003e Carefully screen patients for prior severe hypersensitivity reactions to penicillins, cephalosporins, or other beta-lactam antibiotics.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,2,0\"\u003e\u003cb data-path-to-node=\"22,2,0\" data-index-in-node=\"0\"\u003eRenal Function Monitoring:\u003c\/b\u003e Dosage adjustments are mandatory in patients with renal impairment (\u003cspan class=\"math-inline\" data-math=\"CL_{cr} \u0026lt; 50\\text{ ml\/min}\" data-index-in-node=\"95\"\u003e$CL_{cr} \u0026lt; 50\\text{ ml\/min}$\u003c\/span\u003e).\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,3,0\"\u003e\u003cb data-path-to-node=\"22,3,0\" data-index-in-node=\"0\"\u003eCNS \u0026amp; Seizure Risk:\u003c\/b\u003e Exercise caution in patients with pre-existing central nervous system disorders or epilepsy.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,4,0\"\u003eConsult an attending physician before use during pregnancy or lactation.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n \t\u003cli\u003e\r\\n\u003cp data-path-to-node=\"22,5,0\"\u003eKeep out of reach of children.\u003c\/p\u003e\r\\n\u003c\/li\u003e\r\\n\u003c\/ul\u003e\r\\n\u003ch3 data-path-to-node=\"23\"\u003eStorage Instructions\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"24\"\u003eStore the un-reconstituted dry powder vial in a cool, dry place below 30°C, protected from light and heat. Once reconstituted, the solution should be used immediately or within 2 to 3 hours if kept below 25°C. Do not freeze.\u003c\/p\u003e\r\\n\r\\n\u003ch3 data-path-to-node=\"25\"\u003eManufacturer Information\u003c\/h3\u003e\r\\n\u003cp data-path-to-node=\"26\"\u003eFormulated and manufactured in strict compliance with international pharmaceutical quality standards, dedicated to engineering advanced anti-infective and critical care parenteral therapies that combat antimicrobial resistance and protect patient lives.\u003c\/p\u003e","brand":"My Store","offers":[{"title":"Default Title","offer_id":44164488462395,"sku":null,"price":3500.0,"currency_code":"PKR","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0695\/4899\/8715\/files\/4931070401.jpg?v=1789027868","url":"https:\/\/pharmaservicesgroup.com\/products\/izer-500mg-injection-infusion-broad-spectrum-parenteral-antibacterial-therapy","provider":"Pharma Services Distribution","version":"1.0","type":"link"}